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Nactivation of KLF4 in T cell acute lymphoblastic leukemia promotes the expansion of leukemia cells by activating the Map2k7/Jnk pathway.

ABSTRACT: nactivation of KLF4 in T cell acute lymphoblastic leukemia promotes the expansion of leukemia cells by activating the Map2k7/Jnk pathway.

PROVIDER: PRJNA307539 | ENA |

REPOSITORIES: ENA

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Inactivation of KLF4 in T cell acute lymphoblastic leukemia promotes the expansion of leukemia cells by activating the Map2k7/Jnk pathway. [array]

Project description:Gene expression analysis of bone marrow cells from control and Klf4 deficient T-ALL mice Deletion of Klf4 accelerates NOTCH1-induced leukemia. Analysis provides insight into function of KLF4 in leukemia.

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Inactivation of KLF4 in T cell acute lymphoblastic leukemia promotes the expansion of leukemia cells by activating the Map2k7/Jnk pathway. [ChIP-Seq]

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nactivation of KLF4 in T cell acute lymphoblastic leukemia promotes the expansion of leukemia cells by activating the Map2k7/Jnk pathway.

Project description:This SuperSeries is composed of the SubSeries listed below.

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