Genomics

Dataset Information

0

Xenopus laevis


ABSTRACT: Differential expression analysis of triple knockdown of TBP and TBP-related factors (TKD) in Xenopus laevis embryos at early developmental stage 10.5

ORGANISM(S): Xenopus laevis  

PROVIDER: PRJNA309218 | ENA |

REPOSITORIES: ENA

Dataset's files

Source:
Action DRS
SRR3107014.fastq.gz Fastqsanger.gz
SRR3107015.fastq.gz Fastqsanger.gz
SRR3107016.fastq.gz Fastqsanger.gz
SRR3107017.fastq.gz Fastqsanger.gz
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Publications

Activation of a T-box-Otx2-Gsc gene network independent of TBP and TBP-related factors.

Gazdag Emese E   Jacobi Ulrike G UG   van Kruijsbergen Ila I   Weeks Daniel L DL   Veenstra Gert Jan C GJ  

Development (Cambridge, England) 20160307 8


Embryonic development relies on activating and repressing regulatory influences that are faithfully integrated at the core promoter of individual genes. In vertebrates, the basal machinery recognizing the core promoter includes TATA-binding protein (TBP) and two TBP-related factors. In Xenopus embryos, the three TBP family factors are all essential for development and are required for expression of distinct subsets of genes. Here, we report on a non-canonical TBP family-insensitive (TFI) mechani  ...[more]

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