Genomics

Dataset Information

118

Drosophila melanogaster


ABSTRACT: RNA-seq analysis of Drosophila clock and non-clock neurons reveals neuron-specific cycling and novel candidate neuropeptides

ORGANISM(S): Drosophila melanogaster  

PROVIDER: PRJNA310352 | ENA |

REPOSITORIES: ENA

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Publications

RNA-seq analysis of Drosophila clock and non-clock neurons reveals neuron-specific cycling and novel candidate neuropeptides.

Abruzzi Katharine C KC   Zadina Abigail A   Luo Weifei W   Wiyanto Evelyn E   Rahman Reazur R   Guo Fang F   Shafer Orie O   Rosbash Michael M  

PLoS genetics 20170209 2


Locomotor activity rhythms are controlled by a network of ~150 circadian neurons within the adult Drosophila brain. They are subdivided based on their anatomical locations and properties. We profiled transcripts "around the clock" from three key groups of circadian neurons with different functions. We also profiled a non-circadian outgroup, dopaminergic (TH) neurons. They have cycling transcripts but fewer than clock neurons as well as low expression and poor cycling of clock gene transcripts. T  ...[more]

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