Genomics

Dataset Information

59

Homo sapiens


ABSTRACT: Genome-wide transcriptome profile of CYTOR (LINC00152)-silenced MDA-MB-231 breast cancer cell line

ORGANISM(S): Homo sapiens  

PROVIDER: PRJNA310629 | ENA |

REPOSITORIES: ENA

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Publications


Evidence is emerging that long noncoding RNAs (lncRNAs) may play a role in cancer development, but this role is not yet clear. We performed a genome-wide transcriptional survey to explore the lncRNA landscape across 995 breast tissue samples. We identified 215 lncRNAs whose genes are aberrantly expressed in breast tumors, as compared to normal samples. Unsupervised hierarchical clustering of breast tumors on the basis of their lncRNAs revealed four breast cancer subgroups that correlate tightly  ...[more]

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