Genomics

Dataset Information

0

Homo sapiens


ABSTRACT: PML1: IMR32 vs empty vector IMR32

ORGANISM(S): Homo sapiens  

PROVIDER: PRJNA312586 | ENA |

REPOSITORIES: ENA

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Publications


<label>PURPOSE</label>Neuroblastoma is a childhood malignancy originating from the sympathetic nervous system with a complex biology, prone to metastasize and relapse. High-risk, metastatic cases are explained in part by amplification or mutation of oncogenes, such as MYCN and ALK, and loss of tumor suppressor genes in chromosome band 1p. However, it is fundamental to identify other pathways responsible for the large portion of neuroblastomas with no obvious molecular alterations.<label>EXPERIME  ...[more]

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