Genomics

Dataset Information

0

Homo sapiens


ABSTRACT: DNA methylation signature of human fetal alcohol spectrum disorder

ORGANISM(S): Homo sapiens  

PROVIDER: PRJNA318420 | ENA |

REPOSITORIES: ENA

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Publications


Prenatal alcohol exposure is the leading preventable cause of behavioral and cognitive deficits, which may affect between 2 and 5 % of children in North America. While the underlying mechanisms of alcohol's effects on development remain relatively unknown, emerging evidence implicates epigenetic mechanisms in mediating the range of symptoms observed in children with fetal alcohol spectrum disorder (FASD). Thus, we investigated the effects of prenatal alcohol exposure on genome-wide DNA methylati  ...[more]

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