Dataset Information


Homo sapiens

ABSTRACT: Novel long non-coding RNAs in breast cancer

ORGANISM(S): Homo sapiens  



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Long intergenic non-coding RNA APOC1P1-3 inhibits apoptosis by decreasing α-tubulin acetylation in breast cancer.

Liao X-H XH   Wang J-G JG   Li L-Y LY   Zhou D-M DM   Ren K-H KH   Jin Y-T YT   Lv L L   Yu J-G JG   Yang J-Y JY   Lu Q Q   Zou Q Q   Yu J J   Liu X-P XP   Zhou P P  

Cell death & disease 20160526

Increasing evidence indicates that long non-coding RNAs (lncRNAs) act as important regulatory factors in tumor progression. However, their roles in breast cancer remain largely unknown. In present studies, we identified aberrantly expressed long intergenic non-coding RNA APOC1P1-3 (lincRNA-APOC1P1-3) in breast cancer by microarray, verified it by quantitative real-time PCR, and assessed methylation status in the promoter region by pyrosequencing. We also investigated the biological functions wit  ...[more]

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