Genomics

Dataset Information

0

Homo sapiens


ABSTRACT: caArray_lau-00212: Expression profiles of osteosarcoma that can predict response to chemotherapy

ORGANISM(S): Homo sapiens  

PROVIDER: PRJNA323354 | ENA |

REPOSITORIES: ENA

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Publications


Osteosarcoma is the most common malignant bone tumor in children. After initial diagnosis is made with a biopsy, treatment consists of preoperative chemotherapy followed by definitive surgery and postoperative chemotherapy. The degree of tumor necrosis in response to preoperative chemotherapy is a reliable prognostic factor and is used to guide the choice of postoperative chemotherapy. Patients with tumors, which reveal > or = 90% necrosis (good responders), have a much better prognosis than tho  ...[more]

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