Genomics

Dataset Information

0

Homo sapiens


ABSTRACT: Cord blood hematopoietic cells display altered DNA methylation patterns in preterm birth

ORGANISM(S): Homo sapiens  

PROVIDER: PRJNA323944 | ENA |

REPOSITORIES: ENA

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Publications

Cord blood hematopoietic cells from preterm infants display altered DNA methylation patterns.

de Goede Olivia M OM   Lavoie Pascal M PM   Robinson Wendy P WP  

Clinical epigenetics 20170420


Premature infants are highly vulnerable to infection. This is partly attributable to the preterm immune system, which differs from that of the term neonate in cell composition and function. Multiple studies have found differential DNA methylation (DNAm) between preterm and term infants' cord blood; however, interpretation of these studies is limited by the confounding factor of blood cell composition. This study evaluates the epigenetic impact of preterm birth in isolated hematopoietic cell popu  ...[more]

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