Dataset Information


Homo sapiens

ABSTRACT: Molecular classification of bladder cancer: global mRNA classification versus tumor cell phenotype classification.

ORGANISM(S): Homo sapiens  



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Molecular classification of urothelial carcinoma: global mRNA classification versus tumour-cell phenotype classification.

Sjödahl Gottfrid G   Eriksson Pontus P   Liedberg Fredrik F   Höglund Mattias M  

The Journal of pathology 20170328 1

Global mRNA expression analysis is efficient for phenotypic profiling of tumours, and has been used to define molecular subtypes for almost every major tumour type. A key limitation is that most tumours are communities of both tumour and non-tumour cells. This problem is particularly pertinent for analysis of advanced invasive tumours, which are known to induce major changes and responses in both the tumour and the surrounding tissue. To identify bladder cancer tumour-cell phenotypes and compare  ...[more]

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