Homo sapiens
Ontology highlight
ABSTRACT:
PROVIDER: PRJNA342354 | ENA |
REPOSITORIES: ENA
Similar Datasets
Project description:41 lung adenocarcinoma from never-smokers hybridized on Illumina SNP arrays on 13 HumanCNV370-Quadv3 chips. High-resolution array comparative genomic hybridization analysis of lung adenocarcinoma in 41 never smokers for identification of new minimal common regions (MCR) of gain or loss. The SNP array analysis validated copy-number aberrations and revealed that RB1 and WRN were altered by recurrent copy-neutral loss of heterozygosity.The present study has uncovered new aberrations containing cancer genes. The oncogene FUS is a candidate gene in the 16p region that is frequently gained in never smokers. Multiple genetic pathways defined by gains of MYC, deletions of RB1 and WRN or gains on 7p and 7q are involved in lung adenocarcinoma in never smokers. A 'Cartes d'Identite des Tumeurs' (CIT) project from the French National League Against Cancer (http://cit.ligue-cancer.net) 41 samples hybridized on Illumina SNP arrays. Submitter : Fabien PETEL petelf@ligue-cancer.net . Project leader : Pr Pierre FOURET pierre.fouret@psl.aphp.fr
2011-07-28 | E-TABM-1169 | biostudies-arrayexpress
Project description:Genomic copy number aberrations in primary lung squamous cell carcinoma
| PRJNA184677 | ENA
Project description:Gene Copy Number Aberrations are Associated with Survival in Histological Subgroups of Non-Small Cell Lung Cancer (copy number data)
| PRJNA143019 | ENA
Project description:Micro-scale genomic copy number aberrations as another means of mutagenesis in breast cancer
| PRJNA157149 | ENA
Project description:Copy number profiling of synchronous primary and metastasis of invasive breast cancer
| PRJNA320046 | ENA
Project description:Acquired genomic copy number aberrations and survival in chronic lymphocytic leukemia
| PRJNA144311 | ENA
Project description:Multiple synchronous and metachronous lung tumors are frequently encountered in patients with lung cancer. For treatment purposes it is important to determine, whether or not tumors are clonally related. In other words, whether multiple tumors in a patient are either metastases or multiple primaries. Previous reports show considerable discordance between histopathological and molecular comparison of tumor pairs. The purpose of this study is to compare genome-wide copy number analysis to the classical histological and clinicopathological routine for clonality analysis in a prospective cohort of patients with synchronous or metachronous tumors, of which at least one site occurred in the thorax.
2018-09-20 | GSE87058 | GEO
Project description:Acquired Genomic Copy Number Aberrations and Survival in Adult Acute Myelogenous Leukemia
| PRJNA130995 | ENA
Project description:This SuperSeries is composed of the following subset Series: GSE28571: Gene Copy Number Aberrations are Associated with Survival in Histological Subgroups of Non-Small Cell Lung Cancer (expression data) GSE28572: Gene Copy Number Aberrations are Associated with Survival in Histological Subgroups of Non-Small Cell Lung Cancer (copy number data) Refer to individual Series
2011-11-01 | E-GEOD-28582 | biostudies-arrayexpress
Project description:caArray_gray-00298: Genomic and transcriptional aberrations linked to breast cancer pathophysiologies - Genome Copy Number (Scanning and OncoBAC)
| PRJNA284371 | ENA