Genomics

Dataset Information

2

Macaca mulatta


ABSTRACT: Transcriptome analyses of rhesus monkey pre-implantation embryos reveal a reduced capacity for DNA double strand break (DSB) repair in primate oocytes and early embryos

PROVIDER: PRJNA343030 | ENA |

REPOSITORIES: ENA

Dataset's files

Source:
Action DRS
SRR4242890_1.fastq.gz Fastqsanger.gz
SRR4242890_2.fastq.gz Fastqsanger.gz
SRR4242900_1.fastq.gz Fastqsanger.gz
SRR4242900_2.fastq.gz Fastqsanger.gz
SRR4242910_1.fastq.gz Fastqsanger.gz
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Publications

Transcriptome analyses of rhesus monkey preimplantation embryos reveal a reduced capacity for DNA double-strand break repair in primate oocytes and early embryos.

Wang Xinyi X   Liu Denghui D   He Dajian D   Suo Shengbao S   Xia Xian X   He Xiechao X   Han Jing-Dong J JJ   Zheng Ping P  

Genome research 20170221 4


Preimplantation embryogenesis encompasses several critical events including genome reprogramming, zygotic genome activation (ZGA), and cell-fate commitment. The molecular basis of these processes remains obscure in primates in which there is a high rate of embryo wastage. Thus, understanding the factors involved in genome reprogramming and ZGA might help reproductive success during this susceptible period of early development and generate induced pluripotent stem cells with greater efficiency. M  ...[more]

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