Project description:Array-based genomewide expression (GWE) analyses was used to analyze 17 VSCC samples from untreated patients. The data were validated using relative quantitative PCR.

2016-09-15 | GSE86970 | GEO

UNCOVERING VULVAR CARCINOMA: AN INTEGRATIVE APPROACH [CGH]

Project description:Array-based comparative genomic hybridization (array CGH) analyses was used to analyze 17 VSCC samples from untreated patients. The data were validated using quantitative PCR.

2016-09-15 | GSE86969 | GEO

Integrative array-based approach identifies MZB1 as a frequently methylated putative tumor-suppressor in hepatocellular carcinoma

Project description:This SuperSeries is composed of the following subset Series: GSE35311: Integrative array-based approach identifies MZB1 as a frequently methylated putative tumor-suppressor in hepatocellular carcinoma (expression) GSE35312: Integrative array-based approach identifies MZB1 as a frequently methylated putative tumor-suppressor in hepatocellular carcinoma (MeDIP) Refer to individual Series

2012-03-30 | E-GEOD-35313 | biostudies-arrayexpress

RNA sequencing of invasive vulvar squamous cell carcinoma (VSCC)

Project description:We retrospectively identified cases of invasive vulvar squamous cell carcinoma. Formalin fixed, paraffin embedded tissues samples were retrieved. Sections were confirmed by H&E staining prior to analysis. Sections were processed by ribosomal RNA depletion and RNA-sequencing (KAPA RNA HyperPrep with RiboErase) (HMR). 23 patient samples had RNA of sufficient quality for analysis. HPV status was determined by a consensus of high-risk HPV RNA-ISH and HPV DNA PCR. Only samples that were positive in both assays were considered 'HPV-positive'.

2022-01-01 | GSE183454 | GEO

RNA sequencing of invasive vulvar squamous cell carcinoma (VSCC)

Project description:RNA sequencing of invasive vulvar squamous cell carcinoma (VSCC)

| PRJNA760903 | ENA

Expression data from Vulvar, Cervical, Endometrial Carcinoma tissue

Project description:A growing number of studies on gynecological cancers (GCs) have revealed potential gene markers associated either with the pathogenesis and progression of the disease on representing putative targets for therapy and treatment of cervical (CC), endometrial (EC) and vulvar cancer (VC). However, quite a little overlap is found between these data. In this study we combined data from the three GCs integrating gene expression profile analysis. The meta-analysis including our results and data emerge from other available studies on gynecological malignancies and other cancer types, revealed common properties among them including deregulation of cell cycle, immune response, antiviral response and apoptosis. Total RNA was extracted from physiological and cancer patients from cervix, endometrium and vulvar tissue and was hybridized on Affymetrix HG133_A_2.0 microarray chips corresponding to more than 12.000 uniquely represented genes. A total of 35 samples were used to identify potential biomarkers and signatures in each type of cancer.

2015-07-26 | E-GEOD-63678 | biostudies-arrayexpress

microRNA expression in vulvar melanoma

Project description:microRNA expression in RNA isolated from formalin fixed, paraffin embedded tissue from vulvar melanoma compared to primary cutaneous melanoma

2022-07-16 | GSE208174 | GEO

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