Genomics

Dataset Information

0

Tubular epithelial NF-κB activity regulates acute ischemic kideny injury


ABSTRACT: Tubular epithelial NF-κB activity regulates acute ischemic kideny injury

PROVIDER: PRJNA343239 | ENA |

REPOSITORIES: ENA

altmetric image

Publications


NF-κB is a key regulator of innate and adaptive immunity and is implicated in the pathogenesis of AKI. The cell type-specific functions of NF-κB in the kidney are unknown; however, the pathway serves distinct functions in immune and tissue parenchymal cells. We analyzed tubular epithelial-specific NF-κB signaling in a mouse model of ischemia-reperfusion injury (IRI)-induced AKI. NF-κB reporter activity and nuclear localization of phosphorylated NF-κB subunit p65 analyses in mice revealed that IR  ...[more]

Similar Datasets

2016-09-17 | GSE87023 | GEO
2016-09-17 | GSE87024 | GEO
| S-EPMC5565957 | BioStudies
| S-EPMC8291679 | BioStudies
| S-EPMC8222463 | BioStudies
2017-01-01 | S-EPMC5525899 | BioStudies
| S-EPMC8084703 | BioStudies
| S-EPMC5004652 | BioStudies
| S-EPMC7566738 | BioStudies
| S-EPMC8773493 | BioStudies