Project description:Transcriptional profiling of human lung cancer cell lines A549 comparing control cells transfected with an empty lentiviral expression vector pEZ-Lv201 and A549 cells transfected with a pEZ-Lv201-FENDRR. The latter forms a FENDRR stably over-expressed cell lines. Goal was to to assess the alteration of gene expression profiles caused by FENDRR upregulation.
Project description:The study evaluated the differential gene expression in CBX5 knockdown cells compared to control shRNA expressed HCC827 cells. Briefly, human lung cancer HCC827 cells stably expressing either CBX5 shRNAs or control shRNA were analysed for gene expression.
Project description:Briefly, Human lung cancer HCC827 cells were stably expressing either CBX5 shRNAs or control shRNA were analysed for open chromatin structures using ATAC seq Analysis.