Genomics

Dataset Information

118

Saccharomyces cerevisiae


ABSTRACT: RNAseq and ribosome profiling of yeast cells grown under methionine restriction condition.

ORGANISM(S): Saccharomyces cerevisiae  

PROVIDER: PRJNA356775 | ENA |

REPOSITORIES: ENA

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Publications

A global characterization of the translational and transcriptional programs induced by methionine restriction through ribosome profiling and RNA-seq.

Zou Ke K   Ouyang Qi Q   Li Hao H   Zheng Jiashun J  

BMC genomics 20170217 1


Among twenty amino acids, methionine has a special role as it is coded by the translation initiation codon and methionyl-tRNAi (Met-tRNAi) is required for the assembly of the translation initiation complex. Thus methionine may play a special role in global gene regulation. Methionine has also been known to play important roles in cell growth, development, cancer, and aging. In this work, we characterize the translational and transcriptional programs induced by methionine restriction (MetR) and i  ...[more]

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