Genomics

Dataset Information

0

Homo sapiens


ABSTRACT: RNA sequencing quantitative analysis of exosome miRNAs in plasma in Metastatic renal cell carcinoma (mRCC)

PROVIDER: PRJNA360237 | ENA |

REPOSITORIES: ENA

Dataset's files

Source:
Action DRS
SRR5146230.fastq.gz Fastqsanger.gz
SRR5146240.fastq.gz Fastqsanger.gz
SRR5146250.fastq.gz Fastqsanger.gz
SRR5146260.fastq.gz Fastqsanger.gz
SRR5146231.fastq.gz Fastqsanger.gz
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Publications

Plasma exosomal miRNAs-based prognosis in metastatic kidney cancer.

Du Meijun M   Giridhar Karthik V KV   Tian Yijun Y   Tschannen Michael R MR   Zhu Jing J   Huang Chiang-Ching CC   Kilari Deepak D   Kohli Manish M   Wang Liang L  

Oncotarget 20170722 38


Plasma exosomal miRNAs were evaluated for prognosis in an initial set of 44 metastatic renal cell cancer (mRCC) patients by RNA sequencing. Among ∼3.49 million mappable reads per patient, miRNAs accounted for 93.1% of the mapped RNAs. 227 miRNAs with high abundance were selected for survival analysis. Cox regression analysis identified association of 6 miRNAs with overall survival (OS) (P<0.01, False discovery rate (FDR) < 0.3). Five of the associated miRNAs were quantified in an independent fol  ...[more]

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