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Genes differentially expressed in long-term hematopoietic stem cells with latexin deletion

ABSTRACT: Genes differentially expressed in long-term hematopoietic stem cells with latexin deletion

PROVIDER: PRJNA371777 | ENA |

REPOSITORIES: ENA

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Genes differentially expressed in long-term hematopoietic stem cells with latexin deletion [Long-term hematopoietic stem cells, LT-HSCs]

Project description:Latexin is a hematopoietic stem cell (HSC) regulatory gene. Its deletion leads to the expansion of HSC population. The underlying mechanims are largely unknown. We therefore perfored microarrary analysis in HSCs with (Lxn-/-) and without (wild-type, WT) latexin deletion, and determined genes that were altered by latexin deletion. This led us to identify the molecular mechanims by which latexin regulates HSC function.

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