Project description:During superficial temporal artery (STA)-middle cerebral artery (MCA) anastomoses, micro-samples of both MCA and STA from the patients with MMD (n=4) and internal carotid artery aneurysm (IA) (n=4) were collected. Using microarray technique, transcriptome-wide analyses were performed. Comparing MCA gene expression profile between MMD and IA, we detected 39 up-regulated and 12 down-regulated genes in MMD, showing over 15-fold change with significant difference (P<0.05). Gene set enrichment analysis revealed positive correlation of inflammatory response and negative correlation of collagen formation with MCA of MMD. In addition, by quantitative polymerase chain reaction, significant increased gene expression of TLR2 (P=0.009) and SYK (P=0.04), and decreased gene expression of COL15A1 (P=0.0001) in MCA of MMD were confirmed. While in STA transcriptome analysis, no gene showed significant difference.

2020-02-29 | GSE141022 | GEO

Testicularia cyperi strain:MCA 3645

Project description:Testicularia cyperi MCA 3645 Transcriptome

| PRJNA372885 | ENA

Tilletiopsis washingtonensis strain:MCA 4186

Project description:Tilletiopsis washingtonensis MCA 4816 Transcriptome

| PRJNA265771 | ENA

Pseudomicrostroma glucosiphilum strain:MCA 4718

Project description:Rhodotorula sp. MCA 4718 Transcriptome

| PRJNA265774 | ENA

Meira miltonrushii strain:MCA 3882

Project description:Meira miltonrushii MCA 3882 Transcriptome