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Pervasive epigenetic effects of Drosophila euchromatic transposable elements impact their evolution

ABSTRACT: Pervasive epigenetic effects of Drosophila euchromatic transposable elements impact their evolution

OTHER RELATED OMICS DATASETS IN: GSE94742GSE94741GSE94735

PROVIDER: PRJNA373904 | ENA |

REPOSITORIES: ENA

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Pervasive epigenetic effects of Drosophila euchromatic transposable elements impact their evolution [RNA-seq]

Project description:Pervasive epigenetic effects of Drosophila euchromatic transposable elements impact their evolution [RNA-seq]

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Pervasive epigenetic effects of Drosophila euchromatic transposable elements impact their evolution [RNA-seq]

Project description:We study the relatively unexplored evolutionary consequences of the epigenetic effects of transpoable elements (TEs) by providing the first genome-wide quantification of such effects in wild-derived D. melanogaster and D. simulans strains. Surprisingly, over half of euchromatic TEs show spread of repressive epigenetic marks to nearby DNA, resulting in differential epigenetic states of homologous genic alleles and, in return, selection against TEs. Interestingly, compared to D. melanogaster, the lower TE content in D. simulans is correlated with stronger epigenetic effects of TEs and higher levels of host genetic factors known to promote epigenetic silencing. We conclude that the epigenetic effects of euchromatic TEs, and host genetic factors modulating such effects, play a critical role in the population dynamics of TEs within and between species.

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Pervasive epigenetic effects of Drosophila euchromatic transposable elements impact their evolution

Project description:This SuperSeries is composed of the SubSeries listed below.

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