Project description:Mycobacterium neoaurum (Mn), an efficient sterol consumer, has been modified to transform sterols to produce valuable steroid intermediates, which can be widely used as precursors in the synthesis of steroid hormones.To deepen our understand of the underlying mechanisms of Mn to the in vitro and in vivo environment during growth on a critical carbon source of sterol and accumulation of valuable steroid intermediates, transcriptome studies were performed to characterize the differences between wide-type Mn and various mutant Mn strains for steroid accumulation. Totally, five Mn strains were investigated, including wide-type Mn ATCC25795 cultured without (Mn-C) and with sterol addition (Mn-CC), mutant Mn ATCC25795 strains producing 9OHAD (Mn-9OHAD), ADD (Mn-ADD), and 1,4-HBC (Mn-HBC), respectively.

2018-05-26 | E-MTAB-6789 | biostudies-arrayexpress

Mycolicibacterium neoaurum ATCC 25795

Project description:Mycolicibacterium neoaurum ATCC 25795 Genome sequencing and assembly

| PRJNA244824 | ENA

Mycolicibacterium neoaurum strain:B5-4

Project description:Mycolicibacterium neoaurum strain:B5-4 Genome sequencing and assembly

| PRJNA803772 | ENA

Mycolicibacterium neoaurum strain:B5-4M

Project description:Mycolicibacterium neoaurum strain:B5-4M Genome sequencing and assembly

| PRJNA803773 | ENA

Mycolicibacterium neoaurum VKM Ac-1815D

Project description:Mycolicibacterium neoaurum VKM Ac-1815D Genome sequencing