Project description:The goal of the experiment was to determine the role of H2A deubiquitinase in the nerve injury response in peripheral nerve. A Schwann cell specific knockout of the H2A deubiquitinase (Bap1) was generated to compare with wild type mice.

2022-05-02 | GSE197149 | GEO

Global expression analysis of BAP1 knockdown in transfected 92.1 cells

Project description:Analysis of the effect that reduced BAP1 levels have on global gene expression.The hypothesis tested was that reduction in BAP1 levels would produce changes in gene expression similar to changes observed in class 2 uveal melanomas. Data provided insight into genes that are disrupted with reduced BAP1 levels. Total RNA was isolated from 92.1 cells transfected with either control or BAP1 knockdown constructs for global expression analysis.

2011-01-06 | E-GEOD-24896 | biostudies-arrayexpress

Transcriptome profiles of hematopoietic lineages from BAP1 WT and KO mice

Project description:BAP1 has been studied as a tumor suppressor. Our aim was to characterize genes that were altered in various hematopoietic cell types upon deletion of BAP1. BAP1 WT versus KO cells.

2012-11-07 | E-GEOD-40541 | biostudies-arrayexpress

RNA-seq analysis of peripheral nerve with conditional knockout of Bap1 deubiquitinase.

Project description:RNA-seq analysis of peripheral nerve with conditional knockout of Bap1 deubiquitinase.

| PRJNA809207 | ENA

Expression data from BAP1 depleted cells

Project description:The deubiquitinase BAP1 is a candidate tumor suppressor regulating cell proliferation in human and is required for development in Drosophila. BAP1 is assembled into high molecular weight transcriptional multi-protein complexes. In order to identify potential BAP1 target genes, global mRNA expression profiling using microarrays was conducted. U2OS cells, transfected with a non-target control shRNA or shRNAs targeting BAP1, were selected with puromycin containing medium and then synchronized at the G1/S border to allow comparative analysis of gene expression.

2010-11-05 | E-GEOD-23035 | biostudies-arrayexpress

Global expression analysis of BAP1 knockdown in transfected 92.1 cells

2011-01-06 | GSE24896 | GEO

Transcriptome-wide analysis upon DCP1A knockout

Project description:Transcriptome-wide analysis upon DCP1A knockout

| PRJNA487346 | ENA