Project description:The main objective of this study is to analyze changes in whole-genome transcriptomic profile of ERDMAN_2020(-) strain of Mycobacterium tuberculosis Erdman after ATc-dependent conditional depletion of ERDMAN_2020 by RNA Seq. Total 798 transcripts were found differentially regulated in three biological replicates with log2 fold change ≥ 1 and p-value ≤ 0.05 from. ERDMAN_2020 belongs to MerR family of transcription regulators. Treatment of ERDMAN_2020(-) strain with 50ng/ml ATc for 4 days resulted in accumulation of 338 transcripts and suppression of 460 transcripts, compared to the empty vector control.

2023-07-19 | GSE214729 | GEO

Transcriptome analysis of VapC21 overexpression and deletion in Mycobacterium tuberculosis.

Project description:We report the effects of VapC21 overexpression on Mycobacterium tuberculosis H37Rv strain. The total RNA was isolated from M. tuberculosis harboring either pTetR-int or pTetR-Int-vapC21 the expression was induced with 50 ng/ml anhydrotetracycline for 24 hrs. We report the effect of deletion VapC21 on the transciptional profile of Mycobacterium tuberculosis Erdman strain. For RNA-seq analysis, total RNA was isolated from mid-log phase culture of either parental or △vapC21 mutant strain.

2020-10-05 | GSE154320 | GEO

Mycobacterium tuberculosis str. Erdman = ATCC 35801

Project description:TB-ARC - Taiwan

| PRJNA221521 | ENA

Importance of Atg5, Atg16L1 and Atg7 in mouse bone marrow-derived macrophages infected for 48h with M. tuberculosis Erdman

Project description:To identify cellular pathways altered in autophagy-deficient macrophages during M. tuberculosis infection, we performed 3' Tag-RNA-seq on RNA harvested from Atg5fl/fl LysMcre+/+, Atg16L1fl/fl LysMcre+/+ and Atg7fl/fl LysMcre+/+ mouse bone marrow derived macrophages, and their respective LysMwt/wt control cells, both after 48 hours of infection with M. tuberculosis Erdman and or in mock-infection controls.

2023-03-06 | GSE226503 | GEO

mRNA degradation in Mycobacterium tuberculosis

Project description:This SuperSeries is composed of the following subset Series: GSE36341: mRNA degradation in Mycobacterium tuberculosis under aerobic conditions GSE36342: mRNA degradation in Mycobacterium smegmatis under aerobic conditions GSE36343: mRNA degradation in Mycobacterium tuberculosis during cold and hypoxic stress GSE36344: mRNA degradation in Mycobacterium tuberculosis with DosR ectopically induced Refer to individual Series

2012-03-08 | E-GEOD-36345 | biostudies-arrayexpress

Mycobacterium tuberculosis whiB4 mutant expression

Project description:Comparison of gene expression profile of the whiB4 mutant strain of Mycobacterium tuberculosis with the wild type Mycobacterium tuberculosis H37RV Mtb WhiB4 mutant mRNA was compared with the mRNA of wtMtb H37RV under aerobic conditons

2012-07-24 | GSE37840 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data