Genomics

Dataset Information

235

Mus musculus


ABSTRACT: Single cell RNA-seq of mouse brain astrocyte transcriptomes

ORGANISM(S): Mus musculus  

PROVIDER: PRJNA388076 | ENA |

REPOSITORIES: ENA

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Publications


Cerebrovascular disease is the third most common cause of death in developed countries, but our understanding of the cells that compose the cerebral vasculature is limited. Here, using vascular single-cell transcriptomics, we provide molecular definitions for the principal types of blood vascular and vessel-associated cells in the adult mouse brain. We uncover the transcriptional basis of the gradual phenotypic change (zonation) along the arteriovenous axis and reveal unexpected cell type differ  ...[more]

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