Genomics

Dataset Information

4


ABSTRACT: Creating animal models with natural microbiota to study disease resistance

PROVIDER: PRJNA390686 | ENA |

REPOSITORIES: ENA

Dataset's files

Source:
Action DRS
SRR5690810_1.fastq.gz Fastqsanger.gz
SRR5690810_2.fastq.gz Fastqsanger.gz
SRR5690820_1.fastq.gz Fastqsanger.gz
SRR5690820_2.fastq.gz Fastqsanger.gz
SRR5690830_1.fastq.gz Fastqsanger.gz
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Publications


Laboratory mice, while paramount for understanding basic biological phenomena, are limited in modeling complex diseases of humans and other free-living mammals. Because the microbiome is a major factor in mammalian physiology, we aimed to identify a naturally evolved reference microbiome to better recapitulate physiological phenomena relevant in the natural world outside the laboratory. Among 21 distinct mouse populations worldwide, we identified a closely related wild relative to standard labor  ...[more]

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