Project description:This data is in support of a study entitled "Characterization of PdCP1, a Serine Carboxypeptidase from P. destructans, the Causal Agent of White-nose Syndrome" by Beekman, C. et al. which is submitted and under review. Data will be released upon acceptance of the publication.
Project description:This dataset is provided in support of the identification of a collagen-degrading enzyme secreted by the fungus P. destructans. P. destructans is responsible for the disease white nose syndrome, which has infected and killed millions of North American bats. Our manuscript, titled "Destructin-1 is a Collagen-Degrading Endopeptidase Secreted by P. destructans, the Causative Agent of White-Nose Syndrome", is under review, and the data set will be released upon acceptance.
Project description:This is a training data set for destructin-1 protease digestion of a synthetic peptide library for substrate specificity profiling. Data is related to the following publication:
O'Donoghue AJ, Knudsen GM, Beekman C, Perry JA, Johnson AD, DeRisi JL, Craik
CS, Bennett RJ. "Destructin-1 is a collagen-degrading endopeptidase secreted by
Pseudogymnoascus destructans, the causative agent of white-nose syndrome." Proc Natl Acad Sci U S A. 2015 Jun 16;112(24):7478-83. doi: 10.1073/pnas.1507082112.
Epub 2015 May 5. Erratum in: Proc Natl Acad Sci U S A. 2015 Jun 16;112(24):E3152.
PMCID: PMC4475985.
