Genomics

Dataset Information

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Caenorhabditis elegans


ABSTRACT: Transcriptome analysis reveals molecular anthelmintic effects of procyanidins in C. elegans

ORGANISM(S): Caenorhabditis elegans  

PROVIDER: PRJNA395200 | ENA |

REPOSITORIES: ENA

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Publications

Transcriptome analysis reveals molecular anthelmintic effects of procyanidins in C. elegans.

Spiegler Verena V   Hensel Andreas A   Seggewiß Jochen J   Lubisch Milena M   Liebau Eva E  

PloS one 20170919 9


Worldwide, more than 1 billion people are affected by infestations with soil-transmitted helminths and also in veterinary medicine helminthiases are a severe threat to livestock due to emerging resistances against the common anthelmintics. Proanthocyanidins have been increasingly investigated for their anthelmintic properties, however, except for an interaction with certain proteins of the nematodes, not much is known about their mode of action. To investigate the anthelmintic activity on a mole  ...[more]

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