Genomics

Dataset Information

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Gene and microRNA expression data from African Americans and European Americans with non-small cell lung cancer


ABSTRACT: Gene and microRNA expression data from African Americans and European Americans with non-small cell lung cancer

PROVIDER: PRJNA397223 | ENA |

REPOSITORIES: ENA

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Publications

Comparative Transcriptome Profiling Reveals Coding and Noncoding RNA Differences in NSCLC from African Americans and European Americans.

Mitchell Khadijah A KA   Zingone Adriana A   Toulabi Leila L   Boeckelman Jacob J   Ryan Bríd M BM  

Clinical cancer research : an official journal of the American Association for Cancer Research 20171201 23


Purpose: To determine whether racial differences in gene and miRNA expression translates to differences in lung tumor biology with clinical relevance in African Americans (AAs) and European Americans (EAs).Experimental Design: The NCI-Maryland Case Control Study includes seven Baltimore City hospitals and is overrepresented with AA patients (∼40%). Patients that underwent curative NSCLC surgery between 1998 and 2014 were enrolled. Comparative molecular profiling used mRNA (n = 22 AAs and 19 EAs)  ...[more]

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