Genomics

Dataset Information

0

Homo sapiens


ABSTRACT: Enhanced Inflammatory Transcriptome in the Granulosa Cells of Women With Polycystic Ovarian Syndrome

ORGANISM(S): Homo sapiens  

PROVIDER: PRJNA397337 | ENA |

REPOSITORIES: ENA

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Publications

Enhanced Inflammatory Transcriptome in the Granulosa Cells of Women With Polycystic Ovarian Syndrome.

Adams Jaye J   Liu Zhilin Z   Ren Yi Athena YA   Wun Wan-Song WS   Zhou Wei W   Kenigsberg Shlomit S   Librach Clifford C   Valdes Cecilia C   Gibbons William W   Richards JoAnne J  

The Journal of clinical endocrinology and metabolism 20160526 9


Polycystic ovarian syndrome (PCOS), the most common endocrine disorder of reproductive-aged women, is associated with systemic low-grade inflammation.We propose that increased or altered intrafollicular inflammatory reactions also occur in periovulatory follicles of PCOS patients.Gene profiling and quantitative PCR (qPCR) analyses in granulosa-lutein cells (GCs) collected from PCOS and non-PCOS women undergoing in vitro fertilization were compared with serum and follicular fluid (FF) levels of c  ...[more]

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