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High-throughput deep sequence of zebrafish wild-type and ezh2 mutant embryos

ABSTRACT: High-throughput deep sequence of zebrafish wild-type and ezh2 mutant embryos

PROVIDER: PRJNA407886 | ENA |

REPOSITORIES: ENA

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High-throughput deep sequence of zebrafish wild-type and ezh2 mutant embryos

Project description:To determine the molecular basis for the reduced blood cells in circulation in ezh2 mutant zebrafish, we performed high-throughput sequencing at 28 hpf. Results revealed 893 up-regulated genes and 425 down-regulated genes in the ezh2 mutant zebrafish compared with wild-type zebrafish. We found that some hematopoietic genes are down-regulated in ezh2 mutant zebrafish, which was reconfirmed with qRT-PCR.

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