Project description:Mouse hair follicles undergo synchronized cycles. Cyclical regeneration and hair growth is fueled by stem cells (SCs). During the rest phase, the HF-SCs remain quiescent due to extrinsic inhibitory signals within the niche. As activating cues accumulate, HF-SCs become activated, proliferate, and grows downward to form transient-amplifying matrix progenitor cells. We used ChIP-seq to reveal the genome-wide maps of histone modifications underlying the states of hair follicle stem cells and their transient-amplifying progeny before differentiation. Quiescent hair follicle stem cells (qHF-SCs), activated hair follicle stem cells (aHF-SCs) and transient-amplifying matrix cells (HF-TACs) were FACS-purified for ChIP-sequcencing.

2011-09-02 | E-GEOD-31239 | biostudies-arrayexpress

Genome-wide maps of histone modifications unwind in vivo chromatin states of the hair follicle lineage [ChIP-Seq]

2011-09-02 | GSE31239 | GEO

Genome-wide maps of IRF2 targets

Project description:Genome-wide maps of IRF2 targets

| PRJNA433012 | ENA

Genome-wide maps of HHEX binding

Project description:Genome-wide maps of HHEX binding

| PRJNA615887 | ENA