Project description:mRNA profiles of primary mouse chondrocytes transfected with control siRNA or Sephs1 siRNA were generated by mRNA sequencing. This study provides insights into the role of SEPHS1 in chondrocytes.
Project description:RATIONALE: Studying the genes expressed in samples of tissue from patients with cancer may help doctors identify biomarkers related to cancer.
PURPOSE: This laboratory study is using gene expression profiling to evaluate normal tissue and tumor tissue from patients with colon cancer that has spread to the liver, lungs, or peritoneum.
Project description:Gene expression profiling of mouse articular chondrocytes infected with Ad-C or Ad-Nox4 In this study, we have attempted to explore the effects of Nox4 and have identified numerous genes which are involved in osteoarthritis pathogenesis.
Project description:Gene expression profiling of mouse articular chondrocytes infected with Ad-C or Ad-Rip3 In this study, we have attempted to explore the effects of Rip3 and have identified numerous genes which are involved in osteoarthritis pathogenesis.
Project description:Gene expression profiling of mouse articular chondrocytes infected with Ad-C or Ad-Activin A In this study, we have attempted to explore the effects of Activin A and have identified numerous genes which are involved in osteoarthritis pathogenesis.
Project description:Transcriptional profiling of mouse chondrocytes cells comparing control untreated chondrocytes cells with chondrocytes cells plated in stiff and soft ECM. Goal was to determine the effects of ECM stiffness on gene expression.