Genomics

Dataset Information

2

MiRNA-mediated targeting of human cytomegalovirus reveals biological host and viral targets of IE2


ABSTRACT: miRNA-mediated targeting of human cytomegalovirus reveals biological host and viral targets of IE2

ORGANISM(S): Homo sapiens  

PROVIDER: PRJNA421010 | ENA |

REPOSITORIES: ENA

Dataset's files

Source:
Action DRS
SRR6345380.fastq.gz Fastqsanger.gz
SRR6345371.fastq.gz Fastqsanger.gz
SRR6345381.fastq.gz Fastqsanger.gz
SRR6345372.fastq.gz Fastqsanger.gz
SRR6345382.fastq.gz Fastqsanger.gz
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Publications

miRNA-mediated targeting of human cytomegalovirus reveals biological host and viral targets of IE2.

Møller Rasmus R   Schwarz Toni M TM   Noriega Vanessa M VM   Panis Maryline M   Sachs David D   Tortorella Domenico D   tenOever Benjamin R BR  

Proceedings of the National Academy of Sciences of the United States of America 20180116 5


Human cytomegalovirus (HCMV) impacts more than one-half of the human population owing to its capacity to manipulate the cell and create latent reservoirs in the host. Despite an extensive understanding of HCMV biology during acute infection in fibroblasts, the molecular basis for latency in myeloid cells remains incomplete. This knowledge gap is due largely to the fact that the existing genetic systems require virus rescue in fibroblasts, precluding the study of genes that are essential during a  ...[more]

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