Genomics

Dataset Information

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Multiscale structuring of the E. coli chromosome by nucleoid-associated and condensin proteins


ABSTRACT: Multiscale structuring of the E. coli chromosome by nucleoid-associated and condensin proteins

ORGANISM(S): Escherichia coli str. K-12 substr. MG1655  

PROVIDER: PRJNA421326 | ENA |

REPOSITORIES: ENA

Dataset's files

Source:
Action DRS
SRR6354550_1.fastq.gz Fastqsanger.gz
SRR6354550_2.fastq.gz Fastqsanger.gz
SRR6354560_1.fastq.gz Fastqsanger.gz
SRR6354560_2.fastq.gz Fastqsanger.gz
SRR6354551_1.fastq.gz Fastqsanger.gz
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Publications

Multiscale Structuring of the E. coli Chromosome by Nucleoid-Associated and Condensin Proteins.

Lioy Virginia S VS   Cournac Axel A   Marbouty Martial M   Duigou Stéphane S   Mozziconacci Julien J   Espéli Olivier O   Boccard Frédéric F   Koszul Romain R  

Cell 20180118 4


As in eukaryotes, bacterial genomes are not randomly folded. Bacterial genetic information is generally carried on a circular chromosome with a single origin of replication from which two replication forks proceed bidirectionally toward the opposite terminus region. Here, we investigate the higher-order architecture of the Escherichia coli genome, showing its partition into two structurally distinct entities by a complex and intertwined network of contacts: the replication terminus (ter) region  ...[more]

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