Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Columbia-Yale-Bilkent Study: Genetics Study of Essential Tremor

ABSTRACT: Columbia-Yale-Bilkent Study: Genetics Study of Essential Tremor

PROVIDER: PRJNA422644 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Columbia-Yale-Bilkent Study: Genetics Study of Essential Tremor

Project description:Columbia-Yale-Bilkent Study: Genetics Study of Essential Tremor

| PRJNA422643 | ENA

Next Generation Sequencing Facilitated Cerebellum DNA Methylation Analysis of Essential Tremor Patients

Project description:We report the RRBS-based cerebellum DNA methylation profiling of essential tremor (ET) patients and controls. By obtaining over thirty billion bases of sequence from bisulfited-converted DNA, we generated genome-wide methylation profile of human cerebellum tissue. We identified differential DNA methylation patterns in 735 genes at various gene parts, across 12 ET patients. Many of those differentially methylated CpGs in ET patients are located in upstream regulatory regions of genes. We further found that many differentially methylated genes in ET pateints are associated with neurodegenerative disease. This study provided a framework towards understanding epigenetic alteration in cerebellum of essnetial tremor patients.

2020-02-04 | GSE134426 | GEO

Gene Expression Analysis of Essential Tremor via RNA-sequencing

Project description:RNA-seq evaluation of post-mortem human cerebelllum from 33 patients with diagnosed Essential tremor, compared to 22 age-matched control patients. Two samples were under-sequenced and therefore removed from the final analysis. The raw data has been included in this submission.

2019-07-26 | GSE134878 | GEO

Transcriptomic changes resulting from STK32B overexpression identifies pathways potentially relevant to essential tremor

Project description:We report RNA sequencing of overexpressed STK32B in DAOY cells compared to matched controls, with 200M reads per sample. We identified approximately 4000 differentially expressed genes and potential pathways relevant to essential tremor.

2020-05-13 | GSE150393 | GEO

Identification of Susceptibility Genes for Essential Tremor

Project description:Identification of Susceptibility Genes for Essential Tremor

| PRJNA290967 | ENA

Dissecting the Genetic Underpinnings of Essential Tremor

Project description:Dissecting the Genetic Underpinnings of Essential Tremor

| PRJNA402111 | ENA

Challenges in essential tremor genetics.

Project description: Not available

| S-EPMC4863985 | biostudies-literature

VitGene Generalized Vitiligo Genetics Study

Project description:VitGene Generalized Vitiligo Genetics Study