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Immunological properties of neural crest cells derived from human induced pluripotent stem cells (resting state)

ABSTRACT: Immunological properties of neural crest cells derived from human induced pluripotent stem cells (resting state)

PROVIDER: PRJNA429750 | ENA |

REPOSITORIES: ENA

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Immunological properties of neural crest cells derived from human induced pluripotent stem cells (resting state)

Project description:Collecting primary neural crest cells (NCCs) of a sufficient quantity for some experiments is difficult, because NCCs are embryonic transient tissue and basically they do not proliferate. We successfully induced NCCs from human induced pluripotent stem cells (iPSCs) according to the previously described method with some modifications. iPSCs-derived NCCs (iPSC-NCCs) are reported to have potential for wound healing and expected to be used clinically in the future. However, nobody reported the immunological properties of iPSC-NCCs. It is important to evaluate the immunological properties of iPSC-NCCs before clinical use. We examined gene expression patterns between iPSCs and iPSC-NCCs.

2018-12-01 | GSE109136 | GEO

Immunological properties of neural crest cells derived from human induced pluripotent stem cells (normal vs inflammed condition)

Project description:Collecting primary neural crest cells (NCCs) of a sufficient quantity for some experiments is difficult, because NCCs are embryonic transient tissue and basically they do not proliferate. We successfully induced NCCs from human induced pluripotent stem cells (iPSCs) according to the previously described method with some modifications. iPSCs-derived NCCs (iPSC-NCCs) are reported to have potential for wound healing and expected to be used clinically in the future. However, nobody reported the immunological properties of iPSC-NCCs. It is important to evaluate the immunological properties of iPSC-NCCs before clinical use. In our previous study, we found that iPSC-NCCs have immunosuppressive properties in resting state. In the next step, we examined gene expression patterns between iPSC-NCCs (normal condition) and iPSC-NCCs (inflamed condition).

2018-12-01 | GSE116110 | GEO

Immunological properties of neural crest cells derived from human induced pluripotent stem cells (normal vs inflammed condition)

Project description:Immunological properties of neural crest cells derived from human induced pluripotent stem cells (normal vs inflammed condition)

| PRJNA477291 | ENA

Immunological properties of retinal ganglion cells derived from human induced pluripotent cells

Project description:Immunological properties of retinal ganglion cells derived from human induced pluripotent cells

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Immunological properties of retinal ganglion cells derived from human induced pluripotent cells

Project description:In recent years, research has been conducted to develop retinal ganglion cells (RGCs) transplantation therapies. Although rejection is one of the problems with transplantation therapy, the immunological properties of RGCs have not been clarified. We successfully induced RGCs from human induced pluripotent stem cells (iPSCs). We examined the gene expression patterns of iPS-RGCs using iPSC (a same donor) and peripheral mononuclear blood cells (PBMCs: a same donor) as a control.

2020-10-31 | GSE154544 | GEO

Global ubiquitinome profiling identify Nedd4 as aregulator of Profilin 1 and actin remodeling in neural crest cells

Project description:We utilized quantitative analyses of the proteome, transcriptome, and ubiquitinome to study how ubiquitination and NEDD4 control neural crest cell survival and stem-cell-like properties. We report 276 novel NEDD4 targets in neural crest cells and show that loss of NEDD4 leads to a striking global reduction in specific ubiquitin lysine linkages.

2022-02-08 | PXD024103 | Pride

Immunological Properties of Neural Crest Cells Derived from Human Induced Pluripotent Stem Cells.

Project description: Not available

| S-EPMC6350061 | biostudies-literature

Gene expression profiling of wild type and CNS2-deficient Treg cells in the resting state

Project description:Resting regulatory T cells (CD4+GFP+CD44lowCD62Lhigh) were sorted from the littermates of male Foxp3gfp and Foxp3ΔCNS2-gfp mice. Poly(A)-tailed RNA were amplified and sequenced on an Ion Torrent platform. RNA-seq of WT and CNS2KO regulatory T cells in the resting state

2014-08-14 | E-GEOD-58905 | biostudies-arrayexpress

Resting versus activated T cells

Project description:miRNA profiling of resting and activated T cells Two condition experiment, resting versus activated T cells, measured pooled samples from three independent stimulations

2010-07-07 | E-GEOD-21753 | biostudies-arrayexpress

Embryonic and adult neural crest stem cells

Project description:Cells were isolated from mouse embryonic neural crest stem cells at culture day 2 (NCSC), from day 7 in vitro differentiated progeny (NCP) and day 2 epidermal neural crest stem cells from bulge explants of adult whisker follicles (EPI-NCSC). Keywords: LongSAGE embryonic neural crest stem cells at culture day 2 (NCSC), from day 7 in vitro differentiated progeny (NCP) and day 2 epidermal neural crest stem cells from bulge explants of adult whisker follicles (EPI-NCSC).

2006-04-18 | E-GEOD-4680 | biostudies-arrayexpress

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