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RNA sequencing data of NR-S1, mouse squamous cell carcinoma, and ME-180, human cervical carcinoma for controls and radioresistant cells

ABSTRACT: RNA sequencing data of NR-S1, mouse squamous cell carcinoma, and ME-180, human cervical carcinoma for controls and radioresistant cells

PROVIDER: PRJNA431614 | ENA |

REPOSITORIES: ENA

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RNA sequencing data of NR-S1, mouse squamous cell carcinoma, and ME-180, human cervical carcinoma for controls and radioresistant cells

Project description:We got transcriptome data from NR-S1, mouse squamous cell carcinoma, controls, X-ray resistant cells, C-ion resistant cells. We also performed RNA sequencing on ME-180, human cervical carcinoma, controls and X-ray resistant cells.

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Project description:[original title] Microarray analysis of DNA damage repair gene expression profiles in cervical cancer cells radioresistant to 252Cf neutron and X-rays. The aim of the study was to obtain stable radioresistant sub-lines from the human cervical cancer cell line HeLa by prolonged exposure to 252Cf neutron and X-rays. Radioresistance mechanisms were investigated in the resulting cells using SuperArray Oligo GEArrayÂ® Human DNA Damage Signaling Pathway Microarray. HeLa cells were treated with fractionated 252Cf neutron and X-rays, with a cumulative dose of 75 Gy each, over 8 months, yielding the sub-lines HeLaNR and HeLaXR.Gene expression patterns of the radioresistant sub-lines were studied through microarray analysis

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Differential gene expressions in dose-related radioresistant hypopharyngeal cancer cells

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