Genomics

Dataset Information

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The fate of CD8+ T cells during infection is linked to their developmental origin [Virtual_Memory_following_infection_timestamp]


ABSTRACT: The fate of CD8+ T cells during infection is linked to their developmental origin [Virtual_Memory_following_infection_timestamp]

PROVIDER: PRJNA431923 | ENA |

REPOSITORIES: ENA

Dataset's files

Source:
Action DRS
SRR6517790.fastq.gz Fastqsanger.gz
SRR6517791.fastq.gz Fastqsanger.gz
SRR6517792.fastq.gz Fastqsanger.gz
SRR6517789.fastq.gz Fastqsanger.gz
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Publications


Heterogeneity is a hallmark feature of the adaptive immune system in vertebrates. Following infection, naive T cells differentiate into various subsets of effector and memory T cells, which help to eliminate pathogens and maintain long-term immunity. The current model suggests there is a single lineage of naive T cells that give rise to different populations of effector and memory T cells depending on the type and amounts of stimulation they encounter during infection. Here, we have discovered t  ...[more]

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