Genomics

Dataset Information

432

Trypanosoma cruzi strain:TCC


ABSTRACT: Trypanosoma cruzi strain:TCC Genome sequencing and assembly

ORGANISM(S): Trypanosoma cruzi  

PROVIDER: PRJNA432753 | ENA |

REPOSITORIES: ENA

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Publications

Expanding an expanded genome: long-read sequencing of Trypanosoma cruzi.

Berná Luisa L   Rodriguez Matias M   Chiribao María Laura ML   Parodi-Talice Adriana A   Pita Sebastián S   Rijo Gastón G   Alvarez-Valin Fernando F   Robello Carlos C  

Microbial genomics 20180430 5


Although the genome of Trypanosoma cruzi, the causative agent of Chagas disease, was first made available in 2005, with additional strains reported later, the intrinsic genome complexity of this parasite (the abundance of repetitive sequences and genes organized in tandem) has traditionally hindered high-quality genome assembly and annotation. This also limits diverse types of analyses that require high degrees of precision. Long reads generated by third-generation sequencing technologies are pa  ...[more]

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