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Small RNA Sequencing of Colorectal Adenoma Patient Plasma

ABSTRACT: Small RNA Sequencing of Colorectal Adenoma Patient Plasma

PROVIDER: PRJNA433560 | ENA |

REPOSITORIES: ENA

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Small RNA Sequencing of Colorectal Adenoma Patient Plasma

Project description:In our study, we generated and sequenced small RNA libraries from blood plasma samples. These samples were obtained from patients undergoing colonoscopy and are balanced for age, sex, and self-identified ancestry. From the sequencing data, we derived small-RNA feature counts and performed an analysis for differential expression between patients with and without colorectal adenoma. We found numerous significant associations, including hsa-miR-335-5p and a RNA fragment of the theoretical transcript, AK126744.

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Project description:Pooled samples from human plasma of groups of people with normal intestine, IBD, colorectal adenoma and cancer

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