Latimeria menadoensis
Ontology highlight
ABSTRACT:
PROVIDER: PRJNA43707 | ENA |
REPOSITORIES: ENA
Similar Datasets
Project description:Whole genome resequencing of Indonesian coelacanth Latimeria menadoensis.
| PRJDB1912 | ENA
Project description:Transcriptome analysis of Tanzanian coelacanth Latimeria chalumnae.
| PRJDB1984 | ENA
Project description:Whole genome resequencing of Tanzanian coelacanth Latimeria chalumnae.
| PRJDB2816 | ENA
Project description:Whole genome resequencing of Tanzanian coelacanth Latimeria chalumnae.
| PRJDB2804 | ENA
Project description:Whole genome resequencing of Comoros coelacanth Latimeria chalumnae.
| PRJDB2755 | ENA
Project description:Whole genome resequencing of Tanzanian coelacanth Latimeria chalumnae.
| PRJDB2829 | ENA
Project description:Whole genome resequencing of Tanzanian coelacanth Latimeria chalumnae.
| PRJDB1807 | ENA
Project description:Coelacanth genome sequencing project
| PRJDB500 | ENA
Project description:Bone is an evolutionary novelty of vertebrates, likely to have first emerged as part of ancestral dermal armor that consisted of osteogenic and odontogenic components. Whether these early vertebrate structures arose from mesoderm or neural crest cells has been a matter of considerable debate. To examine the developmental origin of the bony part of the dermal armor, we have performed in vivo lineage tracing in the sterlet sturgeon, a representative of non-teleost ray-finned fish that has retained an extensive postcranial dermal skeleton. The results definitively show that sterlet trunk neural crest cells give rise to osteoblasts of the scutes. Transcriptional profiling further reveals neural crest gene signature in sterlet scutes as well as bichir scales. Finally, histological and microCT analysis of ray-finned fish dermal armor show that their scales and scutes are formed by bone, dentin and hypermineralized covering tissues, in various combinations, that resemble those of the first armored vertebrates. Taken together, our results support a primitive skeletogenic role for the neural crest along the entire body axis, that was later progressively restricted to the cranial region during vertebrate evolution. Thus, the neural crest was a crucial evolutionary innovation driving the origin and diversification of dermal armor along the entire body axis.
2023-06-24 | GSE235280 | GEO
Project description:How modification of gene expression generates novel traits is key to understanding the evolutionary process. Here we investigated the genetic basis for the origin of the piscine gas bladder from lungs of ancestral bony vertebrates. Distinguishing these homologous organs is the direction of budding from the foregut during development; lungs bud ventrally and the gas bladder buds dorsally. We investigated whether this morphological inversion is associated with the molecular inversion of conserved genes regulating lung and gas bladder development. Using laser-capture microdissection and RNA-seq, we assayed transcript abundance and compared expression patterns between dorsal and ventral foregut tissues at three developmental stages spanning gasbladder development. Our focal taxon, bowfin (Amia calva), representing the sistergroup to teleosts, is an early diverging ray-finned fish with a gas bladder. We discovered a number of genes with unknown function during lung development that are differentially expressed during gas bladder development and annotated to functions relevant for organ budding. We also identified several known lung-regulatory genes that exhibit inverted dorsoventral expression during gasbladder development relative to lung development. In particular, we found Tbx5 is strongly expressed in the dorsal mesoderm surrounding the gas bladder during bowfin development, and several interacting genes are co-expressed dorsally with Tbx5. In contrast, in mouse and bichir (Polypterus senegalus), the only ray-finned fish that have lungs, Tbx5 is expressed in the ventral lung mesoderm during lung development. Our data demonstrating dorsoventral inversion of conserved genes suggest that these genes may have contributed to the evolutionary transition between ventral lungs and a dorsal gas bladder in ray-finned fishes.
2021-05-12 | GSE152992 | GEO