Project description:RA signalling regulated endothelial to hematopoietic transition and HSC generation. EB- or FL-derived HSPC were profiled before (d0) or after (d6) 6 days of treatment with 0.2uM AM580 on OP9, and after 6 additional days of expandion of OP9 (d12) without treatment.

2016-05-16 | E-GEOD-76682 | biostudies-arrayexpress

Analysis of MLLT3 genomic distribution and related chromatin features in cultured cord blood hematopoietic stem-progenitor cells, and RNA-seq of MLLT3-L and MLLT3-S overexpressing cultured HSPC compared to non-overexpressing and uncultured FL-HSPC

Project description:This SuperSeries is composed of the SubSeries listed below.

2024-05-31 | GSE252222 | GEO

RNA-seq expression data from FL-HSPCs after HOXA7 knockdown

Project description:HOXA7 regulates FL-HSPC self-renewal in vitro and in vivo. We profiled FL-HSPCs after HOXA7 knockdown, to assess the gene expression programs regulated by HOXA7.

2016-05-16 | GSE76683 | GEO

Study the global mRNA translation changes between SKBR cells overexpressing VIRMA and eGFP control

Project description:In order to determine whether increased m6A abundance coupled with upregulation of transcripts regulating UPR also promote their translation, we first compared levels of key UPR signalling proteins in VIRMA FL-overexpressing SKBR3 cells and eGFP control. To our surprise, none of the key UPR signalling proteins measured showed increased levels in VIRMA FL cells compared to control We then performed ribosome profiling analysis between SKBR cells overexpressing VIRMA FL and eGFP control

2023-08-03 | GSE205873 | GEO

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