Genomics

Dataset Information

0

Transcriptomic analysis of circumvallate papillae (CVP) from lean and DIO mice


ABSTRACT: Transcriptomic analysis of circumvallate papillae (CVP) from lean and DIO mice

PROVIDER: PRJNA437960 | ENA |

REPOSITORIES: ENA

altmetric image

Publications

A chronic LPS-induced low-grade inflammation fails to reproduce in lean mice the impairment of preference for oily solution found in diet-induced obese mice.

Bernard Arnaud A   Ancel Déborah D   Passilly-Degrace Patricia P   Landrier Jean-François JF   Lagrost Laurent L   Besnard Philippe P  

Biochimie 20180810


Diet-induced obesity (DIO) is associated with a decreased oral fat detection in rodents. This alteration has been explained by an impairment of the lipid-mediated signaling in taste bud cells (TBC). However, factors responsible for this defect remain elusive. Diet rich in saturated fatty acids is known to elicit a metabolic inflammation by promoting intestinal permeation to lipopolysaccharides (LPS), Gram-negative bacteria-derived endotoxins. To determine whether a local inflammation of the gust  ...[more]

Publication: 1/2

Similar Datasets

2018-03-13 | GSE111719 | GEO
2021-10-13 | GSE185466 | GEO
| S-EPMC4932145 | BioStudies
| S-EPMC8748953 | BioStudies
2019-01-16 | GSE114604 | GEO
| S-EPMC5796506 | BioStudies
| S-EPMC5995358 | BioStudies
| S-EPMC3610793 | BioStudies
2017-07-25 | MTBLS334 | MetaboLights
2018-12-27 | GSE124356 | GEO