Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Tumor-independent host gene expression changes induced by VEGFR2 antibody

ABSTRACT: Tumor-independent host gene expression changes induced by VEGFR2 antibody

PROVIDER: PRJNA446646 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Tumor-independent host gene expression changes induced by VEGFR2 antibody

Project description:Transcriptome analysis was used to identify tumor-independent changes after treatment with mouse VEGFR2 neutralizing antibody.

2018-03-29 | GSE112467 | GEO

VEGFR2

Project description:VEGFR2 Y949F mutation

| PRJEB44298 | ENA

Tumor-independent host gene expression changes induced by tyrosine kinase inhibitors

Project description:Tumor-independent host gene expression changes induced by tyrosine kinase inhibitors

| PRJNA446647 | ENA

Tumor-independent host gene expression changes induced by PD-1 pathway inhibitors

Project description:Tumor-independent host gene expression changes induced by PD-1 pathway inhibitors

| PRJNA446645 | ENA

VEGFR2 Y949F (lung RNAseq - mice)

Project description:RNA sequencing of lung tissue from transgenic mice in order to investigate the effect of a single tyrosine to phenylalanine exchange in the endothelial receptor VEGFR2 at position Y949. This exchange creates a mouse with unleaky blood vessels which is an advantage in several diseases such as cancer and cardiovascular disease.

2020-06-12 | E-MTAB-9163 | biostudies-arrayexpress

VEGFR2 Y949F (lung RNAseq - mice)

Project description:VEGFR2 Y949F (lung RNAseq - mice)

| PRJEB38638 | ENA

Tumor-independent host gene expression changes induced by tyrosine kinase inhibitors

Project description:Transcriptome analysis was used to identify tumor-independent changes after treatment with different tyrosine kinase inhibitors (TKIs).

2018-03-29 | GSE112466 | GEO

VEGFR2 pY1173 binding partners as identified by shotgun proteomics

Project description:The main goal of the project was to identify proteins binding to vascular endothelial growth factor receptor 2 (VEGFR2) phosphorylation site Y1173. Synthetic peptides, phosphorylated or not, covering different tyrosine phosphorylation sites in VEGFR2 were immobilized and incubated with cell lysates from human umbilical vein endothelial cells. Retained proteins were analyzed by mass spectrometry. Proteins specifically binding to pY1173 peptide were categorized with regard to the presence of an Src Homology 2 (SH2) domain and the main hits were validated in intact cells treated or not with VEGF, for their ability to bind to the activated wild type VEGFR2 but not to a mutant Y1173F VEGFR2. The role of the pY1173 binding partners in VEGF-regulated endothelial biology was further examined in vitro and in vivo.

2023-09-19 | PXD041024 | Pride

Single base mapping of m6A by an antibody-independent method

Project description:Single base mapping of m6A by an antibody-independent method

| PRJNA515628 | ENA

Antibody-independent mechanisms regulate the establishment of chronic Plasmodium infection

Project description:Antibody-independent mechanisms regulate the establishment of chronic Plasmodium infection

| PRJEB15649 | ENA