Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Transfer RNA fragments and microRNAs co-predict circadian-dependent recovery from ischemic stroke [PolyA RNA]

ABSTRACT: Transfer RNA fragments and microRNAs co-predict circadian-dependent recovery from ischemic stroke [PolyA RNA]

PROVIDER: PRJNA449055 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Transfer RNA fragments and microRNAs co-predict circadian-dependent recovery from ischemic stroke

Project description:Transfer RNA fragments and microRNAs co-predict circadian-dependent recovery from ischemic stroke

| PRJNA449054 | ENA

Transfer RNA fragments and microRNAs co-predict circadian-dependent recovery from ischemic stroke [small RNA]

Project description:Transfer RNA fragments and microRNAs co-predict circadian-dependent recovery from ischemic stroke [small RNA]

| PRJNA449056 | ENA

Transfer RNA fragments replace microRNA regulators of the cholinergic post-stroke immune blockade III

Project description:After ischemic stroke, the brain initiates intensive communication with the immune system, and acetylcholine contributes to this process. Stroke triggers peripheral immunosuppression leading to increased susceptibility to infections; and post-stroke pneumonia is linked with poor stroke outcome, but the responsible processes are yet unknown. We discovered a “change of guards” where microRNA levels decreased but small transfer RNA fragments (tRFs) accumulated in post-stroke blood cells. This molecular switch may re-balance acetylcholine signaling in CD14+ monocytes by regulating their gene expression and modulating post-stroke immunity. Our observations point to tRFs as new molecular regulators of post-stroke immune responses that may become potential therapeutic targets.

2020-12-31 | GSE158313 | GEO

Transfer RNA fragments replace microRNA regulators of the cholinergic post-stroke immune blockade II

2020-12-31 | GSE158312 | GEO

Transfer RNA fragments replace microRNA regulators of the cholinergic post-stroke immune blockade I

2020-12-31 | GSE158311 | GEO

Transfer RNA fragments replace microRNA regulators of the cholinergic post-stroke immune blockade

Project description:Transfer RNA fragments replace microRNA regulators of the cholinergic post-stroke immune blockade

| PRJNA664789 | ENA

Transfer RNA fragments replace microRNA regulators of the cholinergic post-stroke immune blockade I

Project description:Transfer RNA fragments replace microRNA regulators of the cholinergic post-stroke immune blockade I

| PRJNA664788 | ENA

Transfer RNA fragments replace microRNA regulators of the cholinergic post-stroke immune blockade III

Project description:Transfer RNA fragments replace microRNA regulators of the cholinergic post-stroke immune blockade III

| PRJNA664793 | ENA

Transfer RNA fragments replace microRNA regulators of the cholinergic post-stroke immune blockade II

Project description:Transfer RNA fragments replace microRNA regulators of the cholinergic post-stroke immune blockade II

| PRJNA664794 | ENA

Long Non-Coding RNA LEENE Promotes Angiogenesis and Ischemic Recovery (RNA-Seq I)

Project description:Vascular endothelial cells play a pivotal role in whole-body homeostasis. To test the function of human long non-coding RNA LEENE in Human umbilical vein endothelial cells (HUVEC), we inhibited LEENE by using a previously validated locked nucleic acid (LNA) GapmeR under pulsatile flow which mimics the physiological state and is characterized by elevated LEENE levels. PolyA-enriched RNA-seq was performed to examine the LEENE-regulated gene expression.

2023-02-08 | GSE205279 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data