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LGP2 virus sensor regulates gene expression network mediated by TRBP-bound microRNAs.

ABSTRACT: LGP2 virus sensor regulates gene expression network mediated by TRBP-bound microRNAs.

PROVIDER: PRJNA449826 | ENA |

REPOSITORIES: ENA

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LGP2 virus sensor regulates gene expression network mediated by TRBP-bound microRNAs.

Project description:To reveal the fuction of cytoplasmic virus sensor protein, LGP2, on RNA silencing, we analyzed gene expression profiles on HeLa WT and LGP2 knockout cells, which were generated with CRISPR/Cas system.

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LGP2 virus sensor regulates gene expression network mediated by TRBP-bound microRNAs.

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LGP2 virus sensor enhances apoptosis by upregulating apoptosis-regulatory genes through TRBP-bound miRNAs during viral infection

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LGP2 virus sensor enhances apoptosis by upregulating apoptosis regulatory genes through TRBP-bound miRNAs during viral infection.

Project description: Not available

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