Genomics

Dataset Information

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Parallel Bimodal Single-cell Sequencing of Transcriptome and Chromatin Accessibility (Mouse single cell ATAC-seq)


ABSTRACT: Parallel Bimodal Single-cell Sequencing of Transcriptome and Chromatin Accessibility (Mouse single cell ATAC-seq)

PROVIDER: PRJNA451119 | ENA |

REPOSITORIES: ENA

Dataset's files

Source:
Action DRS
SRR7047040_1.fastq.gz Fastqsanger.gz
SRR7047040_2.fastq.gz Fastqsanger.gz
SRR7047050_1.fastq.gz Fastqsanger.gz
SRR7047050_2.fastq.gz Fastqsanger.gz
SRR7047060_1.fastq.gz Fastqsanger.gz
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Publications


Joint profiling of transcriptome and chromatin accessibility within single cells allows for the deconstruction of the complex relationship between transcriptional states and upstream regulatory programs determining different cell fates. Here, we developed an automated method with high sensitivity, assay for single-cell transcriptome and accessibility regions (ASTAR-seq), for simultaneous measurement of whole-cell transcriptome and chromatin accessibility within the same single cell. To show the  ...[more]

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