Project description:Analysis of differentially expressed genes in MCF7 cancer cells stably silenced with shlncHAL-2 short-hairpin versus control MCF7 cells stably expressing control shLuc short-hairpin.
Project description:Investigation of whole genome gene expression level changes in TRIB3-silenced MCF7 cells as compared to Control MCF7 cells. Analysis of activity changes of pathways for FOXO1 phosphorylation between TRIB3-silenced and Control MCF7 cells.
Project description:Transcriptional profiling of BLCAP transient knockdown HEK293 cells camparing control shLuc cells with shBLCAP cells. Goal was to determine the effects of BLCAP gene depletion on global gene expression.
Project description:We performed ChIPseq on histone modification marks, transcriptional factors and chromatin architectural proteins in both shBORIS and shLUC resistant Kelly cells.
Project description:CRY2 expression was silenced in MCF7 cells using siRNA oligos, in order to examine the impact of CRY2 knockdown on carcinogenic processes. CRY2 was ~3-fold down-regulated in both replicates, relative to negative control.
Project description:Analysis of differentially expressed genes in MCF7 cancer cells transiently transfected with an expression vector containing the ORF of IKKe and as a control, cells were transfected with a vector containing the ORF of Lacz.