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Transcriptome-wide mapping of RNA:protein interactions of three SR proteins in HeLa cells by iCLIP

ABSTRACT: Transcriptome-wide mapping of RNA:protein interactions of three SR proteins in HeLa cells by iCLIP

PROVIDER: PRJNA454026 | ENA |

REPOSITORIES: ENA

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Transcriptome-wide mapping of RNA:protein interactions of three SR proteins in HeLa cells by iCLIP

Project description:We used GFP-tagged SR proteins expressed at endogenous levels and iCLIP to compare the extent and pattern of SR protein binding to expression-matched lincRNAs and protein-coding RNAs

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Transcriptome-wide mapping of RNA:protein interactions of seven SR proteins and NXF1 in P19 cells by iCLIP

Project description:We used GFP-tagged SR proteins expressed at endogenous levels and iCLIP to identify and compare endogenous RNA targets of individual SR proteins, map the preferential sites of binding, compare binding pattern and binding motifs between family members and to NXF1 and quantify binding of SR proteins and NXF1 to spliced versus unspliced RNAs to study the role of SR proteins in mRNA export via NXF1.

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iCLIP mapping of coilin-RNA interactions in HeLa and P19 cells

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Transcriptome-wide mapping of RNA:protein interactions of three SR proteins in HeLa cells

Project description:Transcriptome-wide mapping of RNA:protein interactions of three SR proteins in HeLa cells

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iCLIP seq reveals distribution of genome-wide SR protein-RNA binding

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2014-11-23 | E-GEOD-63262 | biostudies-arrayexpress

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