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Gene expression in cultured mouse neural progenitor cells

ABSTRACT: Gene expression in cultured mouse neural progenitor cells

PROVIDER: PRJNA454491 | ENA |

REPOSITORIES: ENA

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Gene expression in cultured mouse neural progenitor cells

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Project description:Endogenous neural stem cells reside in the mammalian brain during development and within special niche microenvironments during adulthood. We discovered that endothelial progenitor cell-secreted factors promote the self-renewal of adult mouse NSCs in vivo and identified this protein as ECF-L. We also analyzed molecular signalling networks caused by ECF-L in neural stem cells using global gene expression analysis. Neural stem cells were isolated and expanded from adult mouse brain. Neural stem cells were cultured in the presence or absence of ECF-L in the MHM medium. After the designed period of ECF-L treatment, cells were harvested and RNA was extacted, followed by DNA microarray analysis.

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Gene expression profiles of mouse embryonic neural stem/progenitor cells during astrocyte differentiation

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Expression data from dexamethasone treated mouse embryonic neural progenitor/stem cells isolated from wild type C57Bl/6 or caveolin-1 knockout mice

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2011-09-19 | E-GEOD-22946 | biostudies-arrayexpress

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